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Resting Time Between Behavioral Test #interval

Resting Time Between Behavioral Test

refer to: What Is The Optimum Resting Time Between Behavioral Tasks?

  • The exact days needed for an animal to recover is unknown and not officially set.
  • A general suggestion would be to wait a minimum of 3 days before administering the next behavioral test to an animal. Given that it is not always practical and realistic to wait for one or even two weeks before exposing the animal to the next behavioral task, the researcher should consider applying the most common resting time found in the references.
  • A reduction in the inter-test interval does not have a significant effect on the performance of the subjects on the various tests, except only the performance of the animals on the open-field test. This difference in the open-field results signifies that the neurological test is a rather stressful experience for the animals and should be avoided or if needed it should be performed at the end of a battery.

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oral vs intranasal

Fast onset of action and the analgesic and sedative efficacy of essential oil from Rhizoma Chuanxiong after nasal administration. Pharmazie. 2010 Chuanxiong had faster onset of action as well as better analgesic and sedative efficacy after i.n. administration than given orally. Oil was collected from the condenser, dried over anhydrous sodium sulfate, and the recorded yield of the sample was 0.25% Sedative and anticonvulsant activities of styrax after oral and intranasal administration in mice. Pharm Biol. 2011 styrax had faster onset of action (5 vs. 30 min) and better anticonvulsant efficacy (25, 50 vs. 100, 200 mg/kg) by intranasal route in comparison with that by intragastric route. vehicle (3% Tween 80)  Locomotor activity  Locomotor activity was determined in each mouse after extract administration.  Prior to assay, mice were placed into a locomotor monitoring cage and allowed to habituate to the cage for 5min (0–5min after the administration).  Each mouse was ...